Guide for new and experienced programmers According to Jerome Bruner, learning requires active participation of the learner, experimentation, exploration, and discovery. The book Algorithmic and Computer Programming in Python contains numerous examples, most of which can be practically implemented by the readers, allowing them to become familiar with the Python language so that they ultimately acquire the necessary skills to create their own applications. For this reason, the book is suitable for beginners as well as advanced programmers, high school and secondary school students, students of higher and tertiary educational institutions, amateurs, and professionals in the field. Special care has been taken to also meet the needs of students in the 2nd and 3rd grades of Vocational High Schools (EPAL) in the field of Informatics, in order to prepare them adequately for the national exams. The book is accompanied by free material, available via the Internet, which contains the answers to all exercises as well as the Python programs of the book. Suitable for: • beginners – advanced • educators • high school, secondary school, EPAL students • students – university students • amateurs – professionals.  Aristidis S. Bouras studied at the Department of Electronic Computer Systems of the T.E.I. of Piraeus and the Department of Electrical and Computer Engineering of D.P.T. He has authored books such as computer programming in Python, PHP, C++, C#, Java, Visual Basic.NET, etc. Ioannis Th. Kappos is a graduate of the School of Naval Architects and Marine Engineers of E.M.P. and holds a Ph.D. from D.P.T. He has authored books related to computer operation, the AutoCAD design package, the Internet, aids for High School and Secondary School, etc.